Home : Unsafe Drugs : Fen-Phen

Fen-Phen Side Effects

Name: Fen Phen
Generic: Fenfluramine and dexfenfluramine

Manufacturer: Wyeth-Ayerst Laboratories

Date approved: Redux (dexfenfluramine) approved April 1996
Status: Withdrawn from market
Approved uses: Weight loss
Off-Label uses: N/A
Side effects:
  • Heart Murmurs
  • Heart Valve Leaks
  • Heart Valve Thickening
  • Heart Valve Regurgitation
  • Primary Pulmonary Hypertension
Related topics: Unsafe Drugs, Ephedra, Mesothelioma, Asbestos
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Phen Fen Side Effects

Fen-Phen, also known as Phen Fen, is a cocktail of the drugs fenfluramine and phentermine used to aid weight loss. Fenfluramine and phentermine had been approved for separate, short-term use for about 20 years when the FDA approved Redux or dexfenfluramine in 1996. Fen-Phen was withdrawn from the market after if was found that about 30 percent of users had abnormal echocardiograms. Fen-Phen has been linked to serious cardiac problems, including heart murmurs, heart valve leaks, heart valve thickening, heart valve regurgitation, primary pulmonary hypertension and sometimes death. More than 50,000 lawsuits have been filed by Fen-Phen users against the drugs’ manufacturers.

Dangerous Diet Pills: The Side Effects of Fen-Phen

During the 1990s, doctors began to prescribe fenfluramine (Pondimin®) , dexfenfluramine (Redux™) , and phentermine , more commonly known as Fen-Phen to increase the weight loss effect. Symptoms associated with the use of Fen-Phen include: Shortness of breath. A new heart murmur. read more

Fen-Phen and Redux -- Withdrawn From Market

The diet drugs Fen-Phen (fenfluramine and phentermine), Pondimin (fenfluramine), and Redux (dexfenfluramine) aid in weight loss by altering the serotonin levels in the brain to suppress feelings of hunger. These findings were so serious that the Food and Drug Administration (FDA) withdrew Fen-Phen and Redux from the market in 1997. Problems associated with the use of these diet drugs include: serious heart murmurs, heart valve leaks, thickening of the heart valves, and heart valve regurgitation, which is a build-up of a plaque-like substance on the heart valves. read more

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Fen-Phen Jury Verdicts

______ VERDICT INCLUDING $20,000,000 IN PUNITIVE DAMAGES (case subsequently settles for undisclosed sum) - PRODUCTS LIABILITY - MAJOR PHARMACEUTICAL COMPANY ALLEGEDLY LIABLE FOR PERMANENT HEART DAMAGE SUFFERED BY FEMALE PLAINTIFF ATTRIBUTABLE TO FEN-PHEN DIET DRUG MANUFACTURED AND MARKETED BY THE DEFENDANT - PLAINTIFF ALLEGED THAT THE DEFENDANT AMERICAN HOME PRODUCTS KNEW THAT ITS DRUG WAS UNSAFE AND CONTINUED TO MANUFACTURE AND MARKET THE DRUG REGARDLESS - HEART VALVE DAMAGE.

View the Fen-Phen Jury Verdicts page here

Fen-Phen FDA Information

CDER Index A-F

"FEN-PHEN" UPDATE

View the Fen-Phen FDA Information page here

Fen-Phen News Articles

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Audition au Sénat de M. Jean-Philippe Seta, directeur opérationnel des laboratoires Servier dans l'affaire du Mediator - ElodieValdin sur LePost.fr

View the Fen-Phen News Articles page here

Fen-Phen Newsfeeds

Cardiovascular Risk-benefit Profile of Sibutramine

Embattled fen-phen lawyer in more trouble

View the Fen-Phen Newsfeeds page here

Fen-Phen Useful Web Sites

Anapol Schwarz, Fen-Phen Attorneys

View the Fen-Phen Useful Web Sites page here

Fen-Phen Wikipedia

Fen-phen

Fenfluramine

View the Fen-Phen Wikipedia page here

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